Clinical Risk Factors for Mortality Among Critically Ill Mexican Patients With COVID-19

Clinical Risk Factors for Mortality Among Critically Ill Mexican Patients With COVID-19

Blog Article

Little literature exists about critically ill patients with coronavirus disease 2019 (COVID-19) from Latin America.Here, we aimed to describe the clinical characteristics and mortality risk factors in mechanically ventilated COVID-19 patients from Mexico.For this purpose, we recruited 67 consecutive mechanically ventilated COVID-19 patients which were grouped according to their clinical outcome (survival vs.death).Clinical risk factors for mortality were identified by machine-learning and logistic regression models.

The median age of participants was 42 years and Dog Supplies 65% were men.The most common comorbidity observed was obesity (49.2%).Fever was the most frequent symptom of illness (88%), followed by dyspnea (84%).Multilobe ground-glass opacities were observed in 76% of patients by thoracic computed tomography (CT) scan.

Fifty-two percent of study participants were ventilated in prone position, and 59% required cardiovascular support with norepinephrine.Furthermore, 49% of participants were coinfected with a second pathogen.Two-thirds of COVID-19 patients developed acute kidney injury (AKIN).The mortality of our cohort was 44.7%.

AKIN, uric acid, lactate dehydrogenase (LDH), and a longitudinal increase in the ventilatory ratio were associated with mortality.Baseline PaO2/FiO2 values and a longitudinal recovery of lymphocytes were protective factors against mortality.Our study provides reference Curling - Bags data about the clinical phenotype and risk factors for mortality in mechanically ventilated Mexican patients with COVID-19.